In simple male, the German head of the head of Alexander Zverev was eliminated by France Arthur son in the fourth round.
Zverev lost 3-6 6-3 6-4 at the 17th seeded, leaving only Taylor Fritz and Novak Djokovic as the remaining top-10 in the last eight.
The fourth seeded Djokovic was to play his quarter -final against the 24th American seeded Sebastian Korda later on Wednesday.
However, the match was postponed on Thursday to avoid raping ATP rules prohibiting matches from 11:00 p.m.
The organizers of Miami Open said that the game would be the third match from 1:00 p.m. (5:00 p.m. GMT).
The winner will face Grigor Dimitrov, the 14th seeded Bulgarian, who produced a remarkable mental and physical effort to beat Francisco Cerundolo in Argentina.
Dimitrov, 33, could not convert any of the seven set points in the first set, and looked exhausted in the last stages, before fixing a 6-7 (6-8) 6-4 7-6 victory (7-3).
A few moments after the victory, he breathed strongly and evaluated by a doctor on his chair.
The British pair Julian Cash and Lloyd Glasspool reached the male semi-finals in doubles with a victory of 7-6 (7-1) 3-6 10-8 against Yuki Bhambri of India and Nuno Borges of Portugal.