The Orlando Magic retaliated to upset the Cleveland Cavaliers 108-103 and put an end to the sequence of 16 consecutive Cavs victories.
Orlando recovered from a half-time deficit of 13 points to win, Paolo Banchero marking 24 points and Franz Wagner by adding 22.
Cleveland has already obtained a place in the eliminations at the end of the season and remains well placed to win the seeded from the Eastern Conference.
Meanwhile, the Los Angeles Lakers finished their four-game race with a 107-96 victory against the Phoenix Suns.
LeBron James missed the match with a groin injury, but Luka Doncic was in good shape to play and was the top scorer of the Lakers with 33 points.
Elsewhere, Quentin Grimes scored 28 points against his former team while the 76ers of Philadelphia overcome the Dallas Mavericks 130-125.
The leaders of the West Conference, The Oklahoma City Thunder, recorded a 121-105 victory against the Milwaukee Bucks to improve their record at 56 victories and only 12 defeats, Shai Gilgeous-Alexander striking 31 points and eight assists.
Anthony Edwards scored 41 points while the Minnesota Timberwolves extended their sequence of victories at eight games by beating Utah Jazz 128-102.
The Portland trailblazers retaliated with a 16-point deficit to end a five-game losing race in a 105-102 victory against the Raptors of Toronto.
James Harden scored 31 points for the Clippers in a 123-88 victory against the Charlotte Hornets, while the 28 points of Cameron Johnson helped the Brooklyn Nets to defeat the Atlanta Hawks 122-114.
